Introduction

Alopecia areata is an autoimmune disorder. Hair falls out in small patches on the scalp, beard, and eyebrows. Alopecia areata afflicts approximately 2% of the world’s population. Alopecia areata can occur at any age but it most appears in adolescence. Alopecia may not be life threatening but it is psychologically and socially uncomfortable. Genetic and environmental factors like infections, trauma and stress are responsible for triggering the disease. Hair follicles to be mistakenly attack by the body’s own immune system, and it leads to hair loss. Both CD4 and CD8 T cells are abundant in patient with alopecia areata. There has also been an increase in the production of inflammatory cytokines such as interferon gamma, interleukin 1 alpha and TNF-α. It leads to extreme inflammation in hair follicles in infected individuals. Moreover, the excess production of free radicals can damage hair follicles. This cream-gel has very effective ingredients which also have wonderful effect on treatment and also prevent the disease recurrence. This product by efficient mechanisms inhibits inflammation and oxidative stress in the hair roots, and leads to hair regrowth in patient with alopecia areata.